Signs of Hereditary Cancer
If you or a close relative* have any of the following, a referral to the Genetic Counseling Clinic may be indicated for you:
*Close relatives are: parents, children, brothers, sisters, aunts and uncles, nieces, nephews, grandparents, and grandchildren.
Hereditary Breast and Ovarian Cancer:
- Invasive breast cancer or DCIS diagnosed at or under age 50
- Two or more blood-related individuals with breast cancer
- Male breast cancer
- Ovarian, fallopian tube, or primary peritoneal cancer at any age
- Breast cancer and one or more other separate cancers *
- Breast cancer and large head circumference (57 cm or larger for women, 59 cm or larger for men), and/or mental retardation/autism
- Breast cancer with Eastern European Jewish ancestry, or Hispanic/Latino ancestry from southern Colorado or northern New Mexico
*Cancers that accompany breast cancer in inherited syndromes include: a second new breast cancer, brain, thyroid, pancreatic, & endometrial cancers; lymphoma/leukemia; and adrenal cortical or choroid plexus carcinomas.
Hereditary Colorectal Cancer:
- Colorectal OR uterine cancer diagnosed under age 60
- Two or more separate colorectal cancers in the same person
- Three or more blood related individuals with colorectal or uterine cancer
- Colorectal cancer or uterine cancer and a personal or family history of other cancers*
- Ten or more cumulative gastrointestinal adenomas or hyperplastic polyps
- Hamartomas, juvenile polyps, Peutz-Jeghers polyps
- Pathology of the colorectal tumor shows microsatellite instability or evidence of a mismatch repair defect.
*Cancers/tumors that accompany colorectal cancer in inherited syndromes include: uterine, ovarian, stomach, small intestine, pancreatic, urinary tract cancers, brain tumors, sebaceous adenomas and keratocanthomas.
Other hereditary cancer syndromes:
- An identified inherited/genetic syndrome
- An individual with bilateral or multiple primary cancers or brain tumors
- An individual diagnosed with cancer at an unusually young age
- Three or more blood related family members with the same type of cancer
- Rare cancers such as: medullary thyroid cancer, adrenocortical carcinoma, pheochromocytoma, and paraganglioma
If you feel you may fall into any of these categories, please contact the Genetic Counseling Clinic.